Lipocalin-2 is a pathogenic determinant and biomarker of neuropsychiatric lupus
نویسندگان
چکیده
منابع مشابه
Association of Urinary Lipocalin-2 with Lupus Nephritis
Objective(s): Lupus nephritis (LN) is the main cause of mortality and disability in systemic lupus erythematosus (SLE) patients. Therefore, utilizing a reliable and non-invasive method for serial measurements of renal function seems to be necessary. The aim of this study was to evaluate the role of urinary lipocalin-2 as a biomarker of renal involvement in SLE patients. Materi...
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BACKGROUND One of the challenges of treating patients with lupus nephritis (LN) is to accurately assess disease activity and predict its outcome. Since renal-biopsy cannot be performed routinely, new surrogate biomarkers are needed. METHODS We evaluated neutrophil gelatinase-associated lipocalin (NGAL), to predict renal outcome in LN. Serum and urinary NGAL levels, measured by the enzyme-link...
متن کاملUrinary neutrophil-gelatinase associated lipocalin is a more prognostic biomarker to distinguish antenatal hydronephrosis in neonates
Background: Routine diagnostic methods of Vesicoureteral reflux (VUR) are invasive and can cause exposure to radiation and may increase risk of urinary tract infections. Therefore, introducing reliable, non invasive methods might be more interested in pediatric nephrology. The objective of this perspective case control study was to evaluate the prognostic value of urinary neutrophil-gelatinase ...
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The occurrence of nervous system events in patients with systemic lupus erythematosus (SLE) remains a diagnostic and therapeutic challenge due to the diversity of clinical manifestations, the correction attribution of events to SLE or other causes, and the lack of clinical trial data to facilitate the selection of treatment options. Over the past decade the classifcation and attribution of neur...
متن کاملassociation of urinary lipocalin-2 with lupus nephritis
objective(s): lupus nephritis (ln) is the main cause of mortality and disability in systemic lupus erythematosus (sle) patients. therefore, utilizing a reliable and non-invasive method for serial measurements of renal function seems to be necessary. the aim of this study was to evaluate the role of urinary lipocalin-2 as a biomarker of renal involvement in sle patients. materials and methods:...
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ژورنال
عنوان ژورنال: Journal of Autoimmunity
سال: 2019
ISSN: 0896-8411
DOI: 10.1016/j.jaut.2018.08.005